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PU.1 Suppresses Th2 Cytokine Expression via Silencing of GATA3 Transcription in Dendritic Cells

The transcription factor PU.1 is predominantly expressed in dendritic cells (DCs) and is essential for DC differentiation. Although there are several reports that PU.1 positively regulates the expression of DC-specific genes, whether PU.1 also has a suppressive effect on DCs is largely unknown. Here...

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Detalles Bibliográficos
Autores principales: Yashiro, Takuya, Kubo, Masato, Ogawa, Hideoki, Okumura, Ko, Nishiyama, Chiharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567381/
https://www.ncbi.nlm.nih.gov/pubmed/26361334
http://dx.doi.org/10.1371/journal.pone.0137699