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MyD88 Dependence of Beryllium-Induced Dendritic Cell Trafficking and CD4(+) T Cell Priming

Beryllium exposure results in beryllium hypersensitivity in a subset of exposed individuals, leading to granulomatous inflammation and fibrosis in the lung. In addition to its antigenic properties, beryllium has potent adjuvant activity that contributes to sensitization via unknown pathways. Here, w...

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Detalles Bibliográficos
Autores principales: McKee, Amy S., Mack, Douglas G., Crawford, Frances, Fontenot, Andrew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567547/
https://www.ncbi.nlm.nih.gov/pubmed/25760420
http://dx.doi.org/10.1038/mi.2015.14