Phosphoantigen Burst upon Plasmodium falciparum Schizont Rupture Can Distantly Activate Vγ9Vδ2 T Cells

Malaria induces potent activation and expansion of the Vγ9Vδ2 subpopulation of γδT cells, which inhibit the Plasmodium falciparum blood cycle through soluble cytotoxic mediators, abrogating merozoite invasion capacity. Intraerythrocytic stages efficiently trigger Vγ9Vδ2 T-cell activation and degranu...

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Detalles Bibliográficos
Autores principales: Guenot, Marianne, Loizon, Séverine, Howard, Jennifer, Costa, Giulia, Baker, David A., Mohabeer, Shaneel Y., Troye-Blomberg, Marita, Moreau, Jean-François, Déchanet-Merville, Julie, Mercereau-Puijalon, Odile, Mamani-Matsuda, Maria, Behr, Charlotte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2015
Materias:
Host Response and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567633/
https://www.ncbi.nlm.nih.gov/pubmed/26169273
http://dx.doi.org/10.1128/IAI.00446-15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567633/
https://www.ncbi.nlm.nih.gov/pubmed/26169273
http://dx.doi.org/10.1128/IAI.00446-15

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