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Inhibition of autophagy by 3-MA enhances IL-24-induced apoptosis in human oral squamous cell carcinoma cells

BACKGROUND: Interleukin-24(IL-24), also referred to as melanoma differentiation-associated gene-7(mda-7), is a unique member of the IL-10 gene family, which displays nearly ubiquitous cancer-specific toxicity. The most notable feature of IL-24 is selectively induced growth suppression and apoptosis...

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Detalles Bibliográficos
Autores principales: Li, Jichen, Yang, Dezhao, Wang, Wei, Piao, Songlin, Zhou, Jianyu, Saiyin, Wuliji, Zheng, Changyu, Sun, Hongchen, Li, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567787/
https://www.ncbi.nlm.nih.gov/pubmed/26361755
http://dx.doi.org/10.1186/s13046-015-0211-0