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Up-regulation of activating and inhibitory NKG2 receptors in allogeneic and autologous hematopoietic stem cell grafts

BACKGROUND: Hematopoietic Stem Cell Transplantation (HSCT) is known to induce the inhibitory immune receptor NKG2A on NK cells of donor origin. This occurs in allogeneic recipients, in both the haploidentical and HLA-matched settings. METHODS: To gain further insight, not only NKG2A, but also the ac...

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Detalles Bibliográficos
Autores principales: Picardi, Alessandra, Mengarelli, Andrea, Marino, Mirella, Gallo, Enzo, Benevolo, Maria, Pescarmona, Edoardo, Cocco, Roberta, Fraioli, Rocco, Tremante, Elisa, Petti, Maria Concetta, De Fabritiis, Paolo, Giacomini, Patrizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567793/
https://www.ncbi.nlm.nih.gov/pubmed/26361968
http://dx.doi.org/10.1186/s13046-015-0213-y