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The role of antigen presenting cells in the induction of HIV-1 latency in resting CD4(+) T-cells

BACKGROUND: Combination antiretroviral therapy (cART) is able to control HIV-1 viral replication, however long-lived latent infection in resting memory CD4(+) T-cells persist. The mechanisms for establishment and maintenance of latent infection in resting memory CD4(+) T-cells remain unclear. Previo...

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Detalles Bibliográficos
Autores principales: Kumar, Nitasha A., Cheong, Karey, Powell, David R., da Fonseca Pereira, Candida, Anderson, Jenny, Evans, Vanessa A., Lewin, Sharon R., Cameron, Paul U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567795/
https://www.ncbi.nlm.nih.gov/pubmed/26362311
http://dx.doi.org/10.1186/s12977-015-0204-2