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DDR2 facilitates hepatocellular carcinoma invasion and metastasis via activating ERK signaling and stabilizing SNAIL1

BACKGROUND: Several studies have found that DDR2 is up-regulated in many tumor types and facilitates tumor progression. However, the role of DDR2 in hepatocellular carcinoma (HCC) progression and its downstream signaling pathways remain unclear. METHODS: DDR2 expression was assessed in several cell...

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Detalles Bibliográficos
Autores principales: Xie, Binhui, Lin, Weihao, Ye, Junming, Wang, Xiaonong, Zhang, Bing, Xiong, Shiqiu, Li, Heping, Tan, Guosheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567819/
https://www.ncbi.nlm.nih.gov/pubmed/26362312
http://dx.doi.org/10.1186/s13046-015-0218-6