Nucleated red blood cells impact DNA methylation and expression analyses of cord blood hematopoietic cells

BACKGROUND: Genome-wide DNA methylation (DNAm) studies have proven extremely useful to understand human hematopoiesis. Due to their active DNA content, nucleated red blood cells (nRBCs) contribute to epigenetic and transcriptomic studies derived from whole cord blood. Genomic studies of cord blood h...

Descripción completa

Detalles Bibliográficos
Autores principales: de Goede, Olivia M., Razzaghian, Hamid R., Price, E. Magda, Jones, Meaghan J., Kobor, Michael S., Robinson, Wendy P., Lavoie, Pascal M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567832/
https://www.ncbi.nlm.nih.gov/pubmed/26366232
http://dx.doi.org/10.1186/s13148-015-0129-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567832/
https://www.ncbi.nlm.nih.gov/pubmed/26366232
http://dx.doi.org/10.1186/s13148-015-0129-6

Ejemplares similares