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IL-27 suppresses antimicrobial activity in human leprosy

The mechanisms by which intracellular pathogens trigger immunosuppressive pathways are critical for understanding the pathogenesis of microbial infection. One pathway that inhibits host defense responses involves the induction of type I interferons and subsequently IL-10, yet the mechanism by which...

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Detalles Bibliográficos
Autores principales: Teles, Rosane M. B., Kelly-Scumpia, Kindra M., Sarno, Euzenir N., Rea, Thomas H., Ochoa, Maria T., Cheng, Genhong, Modlin, Robert L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567935/
https://www.ncbi.nlm.nih.gov/pubmed/26030183
http://dx.doi.org/10.1038/jid.2015.195