Cargando…
IL-27 suppresses antimicrobial activity in human leprosy
The mechanisms by which intracellular pathogens trigger immunosuppressive pathways are critical for understanding the pathogenesis of microbial infection. One pathway that inhibits host defense responses involves the induction of type I interferons and subsequently IL-10, yet the mechanism by which...
Autores principales: | Teles, Rosane M. B., Kelly-Scumpia, Kindra M., Sarno, Euzenir N., Rea, Thomas H., Ochoa, Maria T., Cheng, Genhong, Modlin, Robert L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567935/ https://www.ncbi.nlm.nih.gov/pubmed/26030183 http://dx.doi.org/10.1038/jid.2015.195 |
Ejemplares similares
-
MicroRNA-21 targets the vitamin D-dependent antimicrobial pathway in leprosy
por: Liu, Philip T., et al.
Publicado: (2012) -
S100A12 Is Part of the Antimicrobial Network against Mycobacterium leprae in Human Macrophages
por: Realegeno, Susan, et al.
Publicado: (2016) -
The cell fate regulator NUPR1 is induced by Mycobacterium leprae via type I interferon in human leprosy
por: R. Andrade, Priscila, et al.
Publicado: (2019) -
ER Stress Regulates Immunosuppressive Function of Myeloid Derived Suppressor Cells in Leprosy that Can Be Overcome in the Presence of IFN-γ
por: Kelly-Scumpia, Kindra M., et al.
Publicado: (2020) -
A Macrophage Response to Mycobacterium leprae Phenolic Glycolipid Initiates Nerve Damage in Leprosy
por: Madigan, Cressida A., et al.
Publicado: (2017)