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Backbone (1)H, (13)C, and (15)N resonance assignments of the Fc fragment of human immunoglobulin G glycoprotein

The Fc portion of immunoglobulin G (IgG) recruits complements and its cognate receptors, thereby promoting defensive mechanisms in the humoral immune system. These effector functions critically depend on N-glycosylation at the Fc region, which is therefore regarded as a crucial factor in the design...

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Detalles Bibliográficos
Autores principales: Yagi, Hirokazu, Zhang, Ying, Yagi-Utsumi, Maho, Yamaguchi, Takumi, Iida, Shigeru, Yamaguchi, Yoshiki, Kato, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568019/
https://www.ncbi.nlm.nih.gov/pubmed/25291979
http://dx.doi.org/10.1007/s12104-014-9586-7