Modeling the Interaction between β-Amyloid Aggregates and Choline Acetyltransferase Activity and Its Relation with Cholinergic Dysfunction through Two-Enzyme/Two-Compartment Model

The effect of β-amyloid aggregates on activity of choline acetyltransferase (ChAT) which is responsible for synthesizing acetylcholine (ACh) in human brain is investigated through the two-enzyme/two-compartment (2E2C) model where the presynaptic neuron is considered as compartment 1 while both the s...

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Detalles Bibliográficos
Autores principales: Fgaier, Hedia, Mustafa, Ibrahim H. I., Awad, Asmaa A. R., Elkamel, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568057/
https://www.ncbi.nlm.nih.gov/pubmed/26413144
http://dx.doi.org/10.1155/2015/923762

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568057/
https://www.ncbi.nlm.nih.gov/pubmed/26413144
http://dx.doi.org/10.1155/2015/923762

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