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Alleviating neuropathic pain mechanical allodynia by increasing Cdh1 in the anterior cingulate cortex
BACKGROUND: Plastic changes in the anterior cingulate cortex (ACC) are critical in the pathogenesis of pain hypersensitivity caused by injury to peripheral nerves. Cdh1, a co-activator subunit of anaphase-promoting complex/cyclosome (APC/C) regulates synaptic differentiation and transmission. Based...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568074/ https://www.ncbi.nlm.nih.gov/pubmed/26364211 http://dx.doi.org/10.1186/s12990-015-0058-6 |