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Alleviating neuropathic pain mechanical allodynia by increasing Cdh1 in the anterior cingulate cortex

BACKGROUND: Plastic changes in the anterior cingulate cortex (ACC) are critical in the pathogenesis of pain hypersensitivity caused by injury to peripheral nerves. Cdh1, a co-activator subunit of anaphase-promoting complex/cyclosome (APC/C) regulates synaptic differentiation and transmission. Based...

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Detalles Bibliográficos
Autores principales: Tan, Wei, Yao, Wen-Long, Hu, Rong, Lv, You-You, Wan, Li, Zhang, Chuan-Han, Zhu, Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568074/
https://www.ncbi.nlm.nih.gov/pubmed/26364211
http://dx.doi.org/10.1186/s12990-015-0058-6