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Effect of Tongxinluo on Nephrin Expression via Inhibition of Notch1/Snail Pathway in Diabetic Rats

Podocyte injury is an important mechanism of diabetic nephropathy (DN). Accumulating evidence suggests that nephrin expression is decreased in podocyte in DN. Moreover, it has been demonstrated that tongxinluo (TXL) can ameliorate renal structure disruption and dysfunction in DN. However, the effect...

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Detalles Bibliográficos
Autores principales: Cui, Fangqiang, Zou, Dawei, Gao, Yanbin, Zhang, Na, Wang, Jinyang, Xu, Liping, Geng, Jianguo, Li, Jiaoyang, Zhou, Shengnan, Wang, Xinyao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568378/
https://www.ncbi.nlm.nih.gov/pubmed/26417374
http://dx.doi.org/10.1155/2015/424193