Positive and Negative Regulatory Mechanisms for Fine-Tuning Cellularity and Functions of Medullary Thymic Epithelial Cells

Self-tolerant T cells and regulatory T cells develop in the thymus. A wide variety of cell–cell interactions in the thymus is required for the differentiation, proliferation, and repertoire selection of T cells. Various secreted and cell surface molecules expressed in thymic epithelial cells (TECs)...

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Detalles Bibliográficos
Autores principales: Akiyama, Taishin, Tateishi, Ryosuke, Akiyama, Nobuko, Yoshinaga, Riko, Kobayashi, Tetsuya J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568481/
https://www.ncbi.nlm.nih.gov/pubmed/26441966
http://dx.doi.org/10.3389/fimmu.2015.00461

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568481/
https://www.ncbi.nlm.nih.gov/pubmed/26441966
http://dx.doi.org/10.3389/fimmu.2015.00461

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