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IP3R deficit underlies loss of salivary fluid secretion in Sjögren’s Syndrome

The autoimmune exocrinopathy, Sjögren’s syndrome (SS), is associated with secretory defects in patients, including individuals with mild lymphocytic infiltration and minimal glandular damage. The mechanism(s) underlying the secretory dysfunction is not known. We have used minor salivary gland biopsi...

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Detalles Bibliográficos
Autores principales: Teos, Leyla Y., Zhang, Yu, Cotrim, Ana P., Swaim, William, Won, Jon H., Ambrus, Julian, Shen, Long, Bebris, Lolita, Grisius, Margaret, Jang, Shyh-Ing, Yule, David I., Ambudkar, Indu S., Alevizos, Ilias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568516/
https://www.ncbi.nlm.nih.gov/pubmed/26365984
http://dx.doi.org/10.1038/srep13953