Playing POLO-like kinase in NRAS mutant melanoma

NRAS-mutant melanomas are extremely aggressive and highly resistant to currently available therapeutic modalities. Hence, new targets and therapeutic strategies for NRAS-driven melanomas are needed. As blocking NRAS directly has not been possible thus far, targeting downstream NRAS effectors, such a...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Hsin-Yi, Villanueva, Jessie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568563/
https://www.ncbi.nlm.nih.gov/pubmed/26358384
http://dx.doi.org/10.1038/jid.2015.253

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568563/
https://www.ncbi.nlm.nih.gov/pubmed/26358384
http://dx.doi.org/10.1038/jid.2015.253

Ejemplares similares