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Playing POLO-like kinase in NRAS mutant melanoma
NRAS-mutant melanomas are extremely aggressive and highly resistant to currently available therapeutic modalities. Hence, new targets and therapeutic strategies for NRAS-driven melanomas are needed. As blocking NRAS directly has not been possible thus far, targeting downstream NRAS effectors, such a...
Autores principales: | Chen, Hsin-Yi, Villanueva, Jessie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568563/ https://www.ncbi.nlm.nih.gov/pubmed/26358384 http://dx.doi.org/10.1038/jid.2015.253 |
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