Comparison of Efficacy of Endogenous and Exogenous IGF-I in Stimulating Matrix Production in Neonatal and Mature Chondrocytes

OBJECTIVE: The goal of this study was to compare the efficacy of endogenous upregulation of IGF-I by gene therapy and exogenous addition of insulin-like growth factor I (IGF-I) in enhancing proteoglycan synthesis by skeletally mature and neonatal chondrocytes. Chondrocyte transplantation therapy is...

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Detalles Bibliográficos
Autores principales: Aguilar, Izath N., Trippel, Stephen B., Shi, Shuiliang, Bonassar, Lawrence J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568729/
https://www.ncbi.nlm.nih.gov/pubmed/26425264
http://dx.doi.org/10.1177/1947603515578691

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568729/
https://www.ncbi.nlm.nih.gov/pubmed/26425264
http://dx.doi.org/10.1177/1947603515578691

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