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Discovery and Development of Small Molecule Allosteric Modulators of Glycoprotein Hormone Receptors

Glycoprotein hormones, follicle-stimulating hormone (FSH), luteinizing hormone (LH), and thyroid-stimulating hormone (TSH) are heterodimeric proteins with a common α-subunit and hormone-specific β-subunit. These hormones are dominant regulators of reproduction and metabolic processes. Receptors for...

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Detalles Bibliográficos
Autores principales: Nataraja, Selvaraj G., Yu, Henry N., Palmer, Stephen S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568768/
https://www.ncbi.nlm.nih.gov/pubmed/26441832
http://dx.doi.org/10.3389/fendo.2015.00142