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MicroRNA-181c targets Bcl-2 and regulates mitochondrial morphology in myocardial cells

Apoptosis is an important mechanism for the development of heart failure. Mitochondria are central to the execution of apoptosis in the intrinsic pathway. The main regulator of mitochondrial pathway of apoptosis is Bcl-2 family which includes pro- and anti-apoptotic proteins. MicroRNAs are small non...

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Detalles Bibliográficos
Autores principales: Wang, Hongjiang, Li, Jing, Chi, Hongjie, Zhang, Fan, Zhu, Xiaoming, Cai, Jun, Yang, Xinchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568913/
https://www.ncbi.nlm.nih.gov/pubmed/25898913
http://dx.doi.org/10.1111/jcmm.12563