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Epigenetic regulation of miR-129-2 and its effects on the proliferation and invasion in lung cancer cells

MicroRNAs (miRNAs) play a pivotal role in carcinogenesis. Dysregulation of miRNAs, both oncogenic miRNAs and tumour-suppressive miRNAs, is closely associated with cancer development and progression. The levels of miRNAs could be changed epigenetically by DNA methylation in the 5′ untranslated region...

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Detalles Bibliográficos
Autores principales: Xiao, Yingying, Li, Xiaoxia, Wang, Haoli, Wen, Ruiling, He, Juan, Tang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568922/
https://www.ncbi.nlm.nih.gov/pubmed/26081366
http://dx.doi.org/10.1111/jcmm.12597