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Endothelial microparticles reduce ICAM-1 expression in a microRNA-222-dependent mechanism

Endothelial microparticles (EMP) are released from activated or apoptotic endothelial cells (ECs) and can be taken up by adjacent ECs, but their effect on vascular inflammation after engulfment is largely unknown. We sought to determine the role of EMP in EC inflammation. In vitro, EMP treatment sig...

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Detalles Bibliográficos
Autores principales: Jansen, Felix, Yang, Xiaoyan, Baumann, Katharina, Przybilla, David, Schmitz, Theresa, Flender, Anna, Paul, Kathrin, Alhusseiny, Adil, Nickenig, Georg, Werner, Nikos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568925/
https://www.ncbi.nlm.nih.gov/pubmed/26081516
http://dx.doi.org/10.1111/jcmm.12607