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Urokinase receptor and CXCR4 are regulated by common microRNAs in leukaemia cells

The urokinase-type plasminogen activator (uPA) receptor (uPAR) focuses uPA proteolytic activity on the cell membrane, promoting localized degradation of extracellular matrix (ECM), and binds vitronectin (VN), mediating cell adhesion to the ECM. uPAR-bound uPA and VN induce proteolysis-independent in...

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Detalles Bibliográficos
Autores principales: Alfano, Daniela, Gorrasi, Anna, Li Santi, Anna, Ricci, Patrizia, Montuori, Nunzia, Selleri, Carmine, Ragno, Pia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568930/
https://www.ncbi.nlm.nih.gov/pubmed/26082201
http://dx.doi.org/10.1111/jcmm.12617