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Urokinase receptor and CXCR4 are regulated by common microRNAs in leukaemia cells
The urokinase-type plasminogen activator (uPA) receptor (uPAR) focuses uPA proteolytic activity on the cell membrane, promoting localized degradation of extracellular matrix (ECM), and binds vitronectin (VN), mediating cell adhesion to the ECM. uPAR-bound uPA and VN induce proteolysis-independent in...
Autores principales: | Alfano, Daniela, Gorrasi, Anna, Li Santi, Anna, Ricci, Patrizia, Montuori, Nunzia, Selleri, Carmine, Ragno, Pia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568930/ https://www.ncbi.nlm.nih.gov/pubmed/26082201 http://dx.doi.org/10.1111/jcmm.12617 |
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