The cholesterol-binding protein NPC2 restrains recruitment of stromal macrophage-lineage cells to early-stage lung tumours

The tumour microenvironment is known to play an integral role in facilitating cancer progression at advanced stages, but its function in some pre-cancerous lesions remains elusive. We have used the (V600)(E)BRAF-driven mouse lung model that develop premalignant lesions to understand stroma–tumour in...

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Detalles Bibliográficos
Autores principales: Kamata, Tamihiro, Jin, Hong, Giblett, Susan, Patel, Bipin, Patel, Falguni, Foster, Charles, Pritchard, Catrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568947/
https://www.ncbi.nlm.nih.gov/pubmed/26183450
http://dx.doi.org/10.15252/emmm.201404838

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568947/
https://www.ncbi.nlm.nih.gov/pubmed/26183450
http://dx.doi.org/10.15252/emmm.201404838

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