Folate levels modulate oncogene-induced replication stress and tumorigenicity

Chromosomal instability in early cancer stages is caused by replication stress. One mechanism by which oncogene expression induces replication stress is to drive cell proliferation with insufficient nucleotide levels. Cancer development is driven by alterations in both genetic and environmental fact...

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Detalles Bibliográficos
Autores principales: Lamm, Noa, Maoz, Karin, Bester, Assaf C, Im, Michael M, Shewach, Donna S, Karni, Rotem, Kerem, Batsheva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568948/
https://www.ncbi.nlm.nih.gov/pubmed/26197802
http://dx.doi.org/10.15252/emmm.201404824

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568948/
https://www.ncbi.nlm.nih.gov/pubmed/26197802
http://dx.doi.org/10.15252/emmm.201404824

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