Cardiac LXRα protects against pathological cardiac hypertrophy and dysfunction by enhancing glucose uptake and utilization

Pathological cardiac hypertrophy is characterized by a shift in metabolic substrate utilization from fatty acids to glucose, but the molecular events underlying the metabolic remodeling remain poorly understood. Here, we investigated the role of liver X receptors (LXRs), which are key regulators of...

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Detalles Bibliográficos
Autores principales: Cannon, Megan V, Silljé, Herman HW, Sijbesma, Jürgen WA, Vreeswijk-Baudoin, Inge, Ciapaite, Jolita, van der Sluis, Bart, van Deursen, Jan, Silva, Gustavo JJ, de Windt, Leon J, Gustafsson, Jan-Åke, van der Harst, Pim, van Gilst, Wiek H, de Boer, Rudolf A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568954/
https://www.ncbi.nlm.nih.gov/pubmed/26160456
http://dx.doi.org/10.15252/emmm.201404669

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568954/
https://www.ncbi.nlm.nih.gov/pubmed/26160456
http://dx.doi.org/10.15252/emmm.201404669

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