MARCKS-dependent mucin clearance and lipid metabolism in ependymal cells are required for maintenance of forebrain homeostasis during aging

Ependymal cells (ECs) form a barrier responsible for selective movement of fluids and molecules between the cerebrospinal fluid and the central nervous system. Here, we demonstrate that metabolic and barrier functions in ECs decline significantly during aging in mice. The longevity of these function...

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Detalles Bibliográficos
Autores principales: Muthusamy, Nagendran, Sommerville, Laura J, Moeser, Adam J, Stumpo, Deborah J, Sannes, Philip, Adler, Kenneth, Blackshear, Perry J, Weimer, Jill M, Ghashghaei, H Troy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568964/
https://www.ncbi.nlm.nih.gov/pubmed/26010231
http://dx.doi.org/10.1111/acel.12354

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568964/
https://www.ncbi.nlm.nih.gov/pubmed/26010231
http://dx.doi.org/10.1111/acel.12354

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