miR-370 and miR-373 regulate the pathogenesis of osteoarthritis by modulating one-carbon metabolism via SHMT-2 and MECP-2, respectively

The aim of this study was to determine the mechanism underlying the association between one-carbon metabolism and DNA methylation during chronic degenerative joint disorder, osteoarthritis (OA). Articular chondrocytes were isolated from human OA cartilage and normal cartilage biopsied, and the degre...

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Detalles Bibliográficos
Autores principales: Song, Jinsoo, Kim, Dongkyun, Chun, Churl-Hong, Jin, Eun-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568970/
https://www.ncbi.nlm.nih.gov/pubmed/26103880
http://dx.doi.org/10.1111/acel.12363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568970/
https://www.ncbi.nlm.nih.gov/pubmed/26103880
http://dx.doi.org/10.1111/acel.12363

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