Suppression of IGF-I signals in neural stem cells enhances neurogenesis and olfactory function during aging

Downregulation of insulin-like growth factor (IGF) pathways prolongs lifespan in various species, including mammals. Still, the cellular mechanisms by which IGF signaling controls the aging trajectory of individual organs are largely unknown. Here, we asked whether suppression of IGF-I receptor (IGF...

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Detalles Bibliográficos
Autores principales: Chaker, Zayna, Aïd, Saba, Berry, Hugues, Holzenberger, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568972/
https://www.ncbi.nlm.nih.gov/pubmed/26219530
http://dx.doi.org/10.1111/acel.12365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568972/
https://www.ncbi.nlm.nih.gov/pubmed/26219530
http://dx.doi.org/10.1111/acel.12365

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