Pycnogenol Attenuates the Release of Proinflammatory Cytokines and Expression of Perilipin 2 in Lipopolysaccharide-Stimulated Microglia in Part via Inhibition of NF-κB and AP-1 Activation

Over activation of microglia results in the production of proinflammatory agents that have been implicated in various brain diseases. Pycnogenol is a patented extract from French maritime pine bark (Pinus pinaster Aiton) with strong antioxidant and anti-inflammatory potency. The present study invest...

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Detalles Bibliográficos
Autores principales: Fan, Bin, Dun, Sai-Hong, Gu, Jian-Qiu, Guo, Yang, Ikuyama, Shoichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569068/
https://www.ncbi.nlm.nih.gov/pubmed/26367267
http://dx.doi.org/10.1371/journal.pone.0137837

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569068/
https://www.ncbi.nlm.nih.gov/pubmed/26367267
http://dx.doi.org/10.1371/journal.pone.0137837

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