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Reduced NOV/CCN3 Expression Limits Inflammation and Interstitial Renal Fibrosis after Obstructive Nephropathy in Mice

The main hallmark of chronic kidney disease (CKD) is excessive inflammation leading to interstitial tissue fibrosis. It has been recently reported that NOV/CCN3 could be involved in kidney damage but its role in the progression of nephropathies is poorly known. NOV/CCN3 is a secreted multifunctional...

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Detalles Bibliográficos
Autores principales: Marchal, Pierre-Olivier, Kavvadas, Panagiotis, Abed, Ahmed, Kazazian, Chantal, Authier, Florence, Koseki, Haruhiko, Hiraoka, Shuichi, Boffa, Jean-Jacques, Martinerie, Cécile, Chadjichristos, Christos E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569074/
https://www.ncbi.nlm.nih.gov/pubmed/26367310
http://dx.doi.org/10.1371/journal.pone.0137876