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Combination of conditionally replicative adenovirus and standard chemotherapies shows synergistic antitumor effect in pancreatic cancer

Due to devastating prognosis, novel therapies are needed for pancreatic cancer. We are in preparation for a human clinical trial of a conditionally replicative adenovirus (CRAd) we developed. While most patients in the target population are receiving either gemcitabine or 5-fluorouracil chemotherapy...

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Detalles Bibliográficos
Autores principales: Nelson, Amy R, Davydova, Julia, Curiel, David T, Yamamoto, Masato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569096/
https://www.ncbi.nlm.nih.gov/pubmed/19689475
http://dx.doi.org/10.1111/j.1349-7006.2009.01289.x