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Chronic Endotoxemia in Subjects with Type-1 Diabetes Is Seen Much before the Onset of Microvascular Complications

BACKGROUND: Lipopolysaccharide (LPS)/Endotoxin is hypothesized to play an important role in chronic inflammation associated with Type-1 diabetes (T1DM) and its complications. Endotoxin core antibodies (EndoCAb), LPS binding protein (LBP) and soluble CD14 (sCD14) act as modulators of LPS induced acti...

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Detalles Bibliográficos
Autores principales: Aravindhan, Vivekanandhan, Mohan, Viswanathan, Arunkumar, Namasivayam, Sandhya, Sreedharan, Babu, Subash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569180/
https://www.ncbi.nlm.nih.gov/pubmed/26367738
http://dx.doi.org/10.1371/journal.pone.0137618