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Antisense Morpholino Oligonucleotides Reduce Neurofilament Synthesis and Inhibit Axon Regeneration in Lamprey Reticulospinal Neurons

The sea lamprey has been used as a model for the study of axonal regeneration after spinal cord injury. Previous studies have suggested that, unlike developing axons in mammal, the tips of regenerating axons in lamprey spinal cord are simple in shape, packed with neurofilaments (NFs), and contain ve...

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Detalles Bibliográficos
Autores principales: Zhang, Guixin, Jin, Li-qing, Hu, Jianli, Rodemer, William, Selzer, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569278/
https://www.ncbi.nlm.nih.gov/pubmed/26366578
http://dx.doi.org/10.1371/journal.pone.0137670