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Reference Materials for Calibration of Analytical Biases in Quantification of DNA Methylation
Most contemporary methods for the quantification of DNA methylation employ bisulfite conversion and PCR amplification. However, many reports have indicated that bisulfite-mediated PCR methodologies can result in inaccurate measurements of DNA methylation owing to amplification biases. To calibrate a...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569303/ https://www.ncbi.nlm.nih.gov/pubmed/26368560 http://dx.doi.org/10.1371/journal.pone.0137006 |