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Inflammation-induced desmoglein-2 ectodomain shedding compromises the mucosal barrier
Desmosomal cadherins mediate intercellular adhesion and control epithelial homeostasis. Recent studies show that proteinases play an important role in the pathobiology of cancer by targeting epithelial intercellular junction proteins such as cadherins. Here we describe the proinflammatory cytokine-i...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569309/ https://www.ncbi.nlm.nih.gov/pubmed/26224314 http://dx.doi.org/10.1091/mbc.E15-03-0147 |