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Inflammation-induced desmoglein-2 ectodomain shedding compromises the mucosal barrier

Desmosomal cadherins mediate intercellular adhesion and control epithelial homeostasis. Recent studies show that proteinases play an important role in the pathobiology of cancer by targeting epithelial intercellular junction proteins such as cadherins. Here we describe the proinflammatory cytokine-i...

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Detalles Bibliográficos
Autores principales: Kamekura, Ryuta, Nava, Porfirio, Feng, Mingli, Quiros, Miguel, Nishio, Hikaru, Weber, Dominique A., Parkos, Charles A., Nusrat, Asma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569309/
https://www.ncbi.nlm.nih.gov/pubmed/26224314
http://dx.doi.org/10.1091/mbc.E15-03-0147

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