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Positive and negative regulation by SLP-76/ADAP and Pyk2 of chemokine-stimulated T-lymphocyte adhesion mediated by integrin α4β1

Stimulation by chemokines of integrin α4β1–dependent T-lymphocyte adhesion is a crucial step for lymphocyte trafficking. The adaptor Vav1 is required for chemokine-activated T-cell adhesion mediated by α4β1. Conceivably, proteins associating with Vav1 could potentially modulate this adhesion. Correl...

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Detalles Bibliográficos
Autores principales: Dios-Esponera, Ana, Isern de Val, Soledad, Sevilla-Movilla, Silvia, García-Verdugo, Rosa, García-Bernal, David, Arellano-Sánchez, Nohemí, Cabañas, Carlos, Teixidó, Joaquin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569313/
https://www.ncbi.nlm.nih.gov/pubmed/26202465
http://dx.doi.org/10.1091/mbc.E14-07-1246