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Src and cortactin promote lamellipodia protrusion and filopodia formation and stability in growth cones

Src tyrosine kinases have been implicated in axonal growth and guidance; however, the underlying cellular mechanisms are not well understood. Specifically, it is unclear which aspects of actin organization and dynamics are regulated by Src in neuronal growth cones. Here, we investigated the function...

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Detalles Bibliográficos
Autores principales: He, Yingpei, Ren, Yuan, Wu, Bingbing, Decourt, Boris, Lee, Aih Cheun, Taylor, Aaron, Suter, Daniel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569314/
https://www.ncbi.nlm.nih.gov/pubmed/26224308
http://dx.doi.org/10.1091/mbc.E15-03-0142