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Conservation of inner nuclear membrane targeting sequences in mammalian Pom121 and yeast Heh2 membrane proteins

Endoplasmic reticulum–synthesized membrane proteins traffic through the nuclear pore complex (NPC) en route to the inner nuclear membrane (INM). Although many membrane proteins pass the NPC by simple diffusion, two yeast proteins, ScSrc1/ScHeh1 and ScHeh2, are actively imported. In these proteins, a...

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Detalles Bibliográficos
Autores principales: Kralt, Annemarie, Jagalur, Noorjahan B., van den Boom, Vincent, Lokareddy, Ravi K., Steen, Anton, Cingolani, Gino, Fornerod, Maarten, Veenhoff, Liesbeth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569319/
https://www.ncbi.nlm.nih.gov/pubmed/26179916
http://dx.doi.org/10.1091/mbc.E15-03-0184