Differential Relevance of NF-κB and JNK in the Pathophysiology of Hemorrhage/Resususcitation-Induced Liver Injury after Chronic Ethanol Feeding

BACKGROUND: Chronic ethanol (EtOH) abuse worsens pathophysiological derangements after hemorrhagic shock and resuscitation (H/R) that induce hepatic injury and strong inflammatory changes via JNK and NF-κB activation. Inhibiting JNK with a cell-penetrating, protease-resistant peptide D-JNKI-1 after...

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Detalles Bibliográficos
Autores principales: Relja, Borna, Weber, Roxane, Maraslioglu, Miriam, Wagner, Nils, Borsello, Tiziana, Jobin, Christian, Marzi, Ingo, Lehnert, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569329/
https://www.ncbi.nlm.nih.gov/pubmed/26367181
http://dx.doi.org/10.1371/journal.pone.0137875

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569329/
https://www.ncbi.nlm.nih.gov/pubmed/26367181
http://dx.doi.org/10.1371/journal.pone.0137875

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