Intrinsic MyD88-Akt1-mTOR Signaling Coordinates Disparate Tc17 and Tc1 Responses during Vaccine Immunity against Fungal Pneumonia

Fungal infections have skyrocketed in immune-compromised patients lacking CD4(+) T cells, underscoring the need for vaccine prevention. An understanding of the elements that promote vaccine immunity in this setting is essential. We previously demonstrated that vaccine-induced IL-17A(+) CD8(+) T cell...

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Detalles Bibliográficos
Autores principales: Nanjappa, Som Gowda, Hernández-Santos, Nydiaris, Galles, Kevin, Wüthrich, Marcel, Suresh, M., Klein, Bruce S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569330/
https://www.ncbi.nlm.nih.gov/pubmed/26367276
http://dx.doi.org/10.1371/journal.ppat.1005161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569330/
https://www.ncbi.nlm.nih.gov/pubmed/26367276
http://dx.doi.org/10.1371/journal.ppat.1005161

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