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ER Stress Mediates TiAl(6)V(4) Particle-Induced Peri-Implant Osteolysis by Promoting RANKL Expression in Fibroblasts

Wear particle-induced osteolysis is a major cause of aseptic loosening, which is one of the most common reasons for total hip arthroplasty (THA) failure. Previous studies have shown that the synovial fibroblasts present in the periprosthetic membrane are important targets of wear debris during osteo...

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Detalles Bibliográficos
Autores principales: Wang, Zhenheng, Liu, Naicheng, Shi, Tongguo, Zhou, Gang, Wang, Zhenzhen, Gan, Jingjing, Guo, Ting, Qian, Hongbo, Bao, Nirong, Zhao, Jianning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569331/
https://www.ncbi.nlm.nih.gov/pubmed/26366858
http://dx.doi.org/10.1371/journal.pone.0137774