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Differential Expression of Non-Shelterin Genes Associated with High Telomerase Levels and Telomere Shortening in Plasma Cell Disorders

Telomerase, shelterin proteins and various interacting factors, named non-shelterin proteins, are involved in the regulation of telomere length (TL). Altered expression of any of these telomere-associated genes can lead to telomere dysfunction, causing genomic instability and disease development. In...

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Detalles Bibliográficos
Autores principales: Panero, Julieta, Stella, Flavia, Schutz, Natalia, Fantl, Dorotea Beatriz, Slavutsky, Irma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569359/
https://www.ncbi.nlm.nih.gov/pubmed/26366868
http://dx.doi.org/10.1371/journal.pone.0137972