Multimer Formation Explains Allelic Suppression of PRDM9 Recombination Hotspots

Genetic recombination during meiosis functions to increase genetic diversity, promotes elimination of deleterious alleles, and helps assure proper segregation of chromatids. Mammalian recombination events are concentrated at specialized sites, termed hotspots, whose locations are determined by PRDM9...

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Detalles Bibliográficos
Autores principales: Baker, Christopher L., Petkova, Pavlina, Walker, Michael, Flachs, Petr, Mihola, Ondrej, Trachtulec, Zdenek, Petkov, Petko M., Paigen, Kenneth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569383/
https://www.ncbi.nlm.nih.gov/pubmed/26368021
http://dx.doi.org/10.1371/journal.pgen.1005512

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569383/
https://www.ncbi.nlm.nih.gov/pubmed/26368021
http://dx.doi.org/10.1371/journal.pgen.1005512

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