Cargando…

Ergot Alkaloids (Re)generate New Leads as Antiparasitics

Praziquantel (PZQ) is a key therapy for treatment of parasitic flatworm infections of humans and livestock, but the mechanism of action of this drug is unresolved. Resolving PZQ-engaged targets and effectors is important for identifying new druggable pathways that may yield novel antiparasitic agent...

Descripción completa

Detalles Bibliográficos
Autores principales: Chan, John D., Agbedanu, Prince N., Grab, Thomas, Zamanian, Mostafa, Dosa, Peter I., Day, Timothy A., Marchant, Jonathan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569474/
https://www.ncbi.nlm.nih.gov/pubmed/26367744
http://dx.doi.org/10.1371/journal.pntd.0004063