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Ergot Alkaloids (Re)generate New Leads as Antiparasitics
Praziquantel (PZQ) is a key therapy for treatment of parasitic flatworm infections of humans and livestock, but the mechanism of action of this drug is unresolved. Resolving PZQ-engaged targets and effectors is important for identifying new druggable pathways that may yield novel antiparasitic agent...
Autores principales: | Chan, John D., Agbedanu, Prince N., Grab, Thomas, Zamanian, Mostafa, Dosa, Peter I., Day, Timothy A., Marchant, Jonathan S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569474/ https://www.ncbi.nlm.nih.gov/pubmed/26367744 http://dx.doi.org/10.1371/journal.pntd.0004063 |
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