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Drosophila Eye Model to Study Neuroprotective Role of CREB Binding Protein (CBP) in Alzheimer’s Disease

BACKGROUND: The progressive neurodegenerative disorder Alzheimer’s disease (AD) manifests as loss of cognitive functions, and finally leads to death of the affected individual. AD may result from accumulation of amyloid plaques. These amyloid plaques comprising of amyloid-beta 42 (Aβ42) polypeptides...

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Detalles Bibliográficos
Autores principales: Cutler, Timothy, Sarkar, Ankita, Moran, Michael, Steffensmeier, Andrew, Puli, Oorvashi Roy, Mancini, Greg, Tare, Meghana, Gogia, Neha, Singh, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569556/
https://www.ncbi.nlm.nih.gov/pubmed/26367392
http://dx.doi.org/10.1371/journal.pone.0137691